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泌尿系统肿瘤的化疗与免疫治疗:高级治疗师指南
$61.45
随着近年来肿瘤预防与治疗理念的提升,临床诊断和治疗技术的快速持续发展,恶性肿瘤患者的生存期也随之不断延长。泌尿男性生殖系统肿瘤是一系列泌尿系统和男性生殖系统肿瘤的交叉,包括发病率较高的前列腺肿瘤、尿路上皮肿瘤和肾脏肿瘤,以及睾丸肿瘤、阴茎肿瘤等少见肿瘤。Thomas Jefffferson 大学 Sidney Kimmel 癌症中心在多学科团队中引入高级治疗师理念,参与多学科团队并负责协调治疗。本指南虽然是以高级治...
随着近年来肿瘤预防与治疗理念的提升,临床诊断和治疗技术的快速持续发展,恶性肿瘤患者的生存期也随之不断延长。泌尿男性生殖系统肿瘤是一系列泌尿系统和男性生殖系统肿瘤的交叉,包括发病率较高的前列腺肿瘤、尿路上皮肿瘤和肾脏肿瘤,以及睾丸肿瘤、阴茎肿瘤等少见肿瘤。Thomas Jefffferson 大学 Sidney Kimmel 癌症中心在多学科团队中引入高级治疗师理念,参与多学科团队并负责协调治疗。本指南虽然是以高级治疗师为读者群,但内容紧跟泌尿男性生殖系统肿瘤治疗的最新进展,对于国内广大关注泌尿男性生殖系统肿瘤治疗的同道亦会有积极的帮助。
本书引进自Springer出版社,是一部重点向泌尿科及相关科室临床医生介绍泌尿系统恶性肿瘤化疗与免疫治疗方案的实用指南。全书共25章,旨在让临床从业者热悉泌尿系统恶性肿瘤的全身治疗选择和医疗管理,包括前列腺癌、膀胱癌、肾细胞癌、翠丸癌和阴茎癌,系统介绍了各类型肿瘤的化疗、放射治疗、免疫治疗、粑向治疗、雄激素剥夺治疗及一些新型疗法。本书由该领域的引领型专家团队撰写,回顾了当前泌尿生殖系统恶性肿瘤的化疗和免疫治疗方案,并讨论了适应证、治疗效果和不良反应,以及相关临床试验的内容,可作为泌尿科医生及相关专业技术人员的实用参考书。
何志嵩,北京大学第一医院泌尿外科主任医师、教授,北京大学第一医院泌尿外科科主任,北京大学泌尿外科研究所副所长
目录绪 篇第1章 高级治疗师与泌尿系统肿瘤治疗的融合第一篇 前列腺癌第2章 总论及前列腺癌主动监测一、背景二、流行病学三、危险因素四、症状和体征五、PSA和筛查六、诊断评估七、病理八、分期九、风险分层十、主动监测第3章 初始前列腺癌治疗后患者的随访和后续治疗一、背景二、监测种类三、生化复发的监测四、危险分层和进一步检查五、复发的证据六、总结第4章 前列腺癌根治术及术后生存率一、前列腺癌根治术二、RP术后的存活率第5章 前列腺癌的多模式治疗方案一、治疗选择二、术后放疗三、基因组学第6章前列腺癌的放疗一、放疗技术二、基于前列腺癌分期的放疗三、剂量分割模式四、减症放疗五、放疗联合ADT治疗六、不良反应:识别、治疗和管理七、放疗后生存情况八、总结第7章雄激素剥夺治疗一、背景二、功能机制三、治疗药物四、抗雄激素撤退五、不良反应管理六、健康的生活方式七、患者咨询八、二线激素药物第8章 第二代雄激素靶向药物一、第二代雄激素靶向药物二、阿比特龙、恩扎卢胺、阿帕他胺及达罗他胺的用法、适应证及不良反应三、总结第9章前列腺癌的化疗一、转移性激素敏感性前列腺癌(mHSPC)二、转移性去势抵抗性前列腺癌(mCRPC)三、转移性神经内分泌四、化疗五、紫杉烷类衍生物的不良反应处理六、总结第10章 前列腺癌的放射性药物一、放射性药物概述二、锶-89三、钐-153四、镭-223五、新的发展方向和结论第11章 前列腺癌的免疫治疗和新型药物治疗一、治疗性疫苗二、免疫调节药物/检查点抑制药三、PARP抑制药四、联合治疗第二篇 膀胱癌第12章 膀胱癌:概述、流行病学、临床表现和诊断一、膀胱癌概况及流行病学二、尿路上皮癌:概述三、分期四、尿路上皮癌的组织学变异五、非尿路上皮恶性肿瘤六、膀胱癌进展的危险因素七、促使膀胱癌进展的药物/化学品八、膀胱癌的危险因素——年龄、性别和遗传九、死亡十、初步表现和诊断十一、体格检查十二、诊断实验第13章 非肌层浸润性尿路上皮癌的膀胱腔内治疗一、膀胱内化疗二、膀胱腔内治疗的临床应用三、治疗关键点第14章 膀胱癌:肌层浸润性疾病、新辅助化疗和根治性膀胱切除术一、新辅助化疗二、新辅助免疫治疗三、不良反应四、根治性膀胱切除术五、手术方式六、围术期患者教育七、管控手术并发症八、尿流改道九、治疗后生存十、总结第15章保膀胱同步放化疗一、适应证和作用机制二、TMT流程图 三、随访四、未来的方向第16章 转移性膀胱癌与顺铂化疗的应用一、诊断/初步评估二、治疗选择三、治疗相关的毒性反应五、监测疾病治疗反应第17章 转移性尿路上皮癌的免疫治疗一、尿路上皮癌全身免疫治疗概述二、转移性尿路上皮癌治疗药物三、总结第18章 转移性尿路上皮癌的新型和实验性治疗一、近期的进展二、分子标记与基因组和靶向治疗三、FGFR抑制药四、ErbB五、总结第19章上尿路尿路上皮癌一、发病二、与膀胱癌的关联三、病因四、表现五、诊断六、治疗和随访第三篇 肾 癌第20章 肾癌及其治疗一、首诊二、肾肿瘤的种类三、肾细胞癌的概述四、影像学五、肾穿刺9六、分期…七、消融和冷冻治疗八、肾部分切除术vs.根治性肾切除术:RENAL评分九、放疗(XRT)十、化疗十一、抗血管生成药物治疗十二、免疫治疗十三、人群筛查第21章转移性肾细胞癌的靶向治疗一、背景二、酪氨酸激酶抑制药三、抗血管内皮生长因子(VEGF)抗体四、哺乳动物雷帕霉素靶蛋白(mTOR)五、转移性肾细胞癌TKI治疗总结六、治疗不良反应的管理第22章 转移性肾癌的免疫治疗一、背景二、IL-2三、干扰素a-2a四、免疫调节药及检查点抑制药五、总结第23章肾细胞癌新型治疗一、纳武单抗二、伊匹木单抗三、卡博替尼四、其他新型药物五、肿瘤和生物标志物六、总结第四篇 其他恶性肿瘤第24章 睾丸癌一、临床表现和体征二、流行病学三、危险因素四、筛查五、早期检查六、治疗第25章 阴茎癌一、危险因素和预防二、自然病程三、肿瘤分期四、阴茎癌的化疗五、靶向治疗六、免疫治疗七、总结
本书的编写理念来自泌尿肿瘤学家、泌尿生殖肿瘤学家、泌尿生殖放射肿瘤学家及多方机构的高级治疗师持续性的协作。本书体现了专业间双向指导、共同努力和坚定合作情谊的巅峰。希望本书能够提供有用的信息和指导,帮助泌尿男性生殖系统肿瘤患者获得最佳的治疗效果。
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