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慢性便秘诊治进展
$57.35
书中内容不仅包含慢性便秘的病因和发病机制等基础理论研究的进展,还有微生态治疗、药物治疗和中医药治疗的相关内容,尤其关注外科手术在慢性便秘治疗方面的新突破。本书以中青年专家作为创作主体,由资深专家作点睛之笔,不仅饱含了青年学者对疾病的深刻理解与感悟,更凝聚了众位该领域全国*大师的毕生经验。因此,本书无论从内容还是形式上均体现了规范与探索、传承与创新的特色。本书的出版将为广大一线临床工作者提供参考,进而更好地服务于广大患者。同时,本书通俗易懂,也为广大患者正确认识疾病并Z终战胜疾病提供了有益帮助。
全书分上、下两篇,共 10 章。上篇概论部分,简明介绍了慢性便秘的临床基础、诊治概况及儿童慢性便秘的相关内容;下篇则对慢性便秘的Z新研究及诊治进展进行了具体阐释,不仅包含慢性便秘的发病机制、影像诊断、外科治疗、中西医诊疗策略、综合诊治等方面的研究进展,还对肠道菌群关系、生物反馈与电刺激等近年来的研究热点做了细致介绍。书末还特意汇编了慢性便秘相关诊治指南,以便读者随时查阅。本书内容实用,阐释系统,可为消化科、胃肠科、肛肠外科,妇科、盆底外科等从事慢性便秘一线工作临床医生和研究者提供参考,亦可帮助更多有兴趣的读者了解慢性便秘的相关知识与进展。
黄忠诚 主任医师、教授、硕士研究生导师,湖南省人民医院学科顾问,湖南省肛肠疾病诊疗中心主任,湖南省肛肠外科医疗质量控制中心主任,中国医师协会肛肠医师分会肛肠疾病专家委员会主任委员,中国医师协会中西结合分会肛肠疾病专业委员会副主任委员,中国医师协会结直肠肿瘤专委会早诊早治专委会副主任委员,中华医学会结直肠肛门外科学组委员,湖南省医学会结直肠肛门外科学组组长,中国医师协会结直肠肿瘤分会常委,中国医师协会肛肠医师分会常委,中国抗癌协会大肠癌专业委员会常委,中国医师协会外科分会肛肠外科专业委员会常务委员,中国便秘联谊会副会长,中华中医药学会肛肠分会常务理事兼副秘书长,中国中西结合学会大肠肛门疾病专业委员会委员,湖南省医师协会外科医师分会副会长,湖南省普通外科专业委员会副主任委员,国家执业医师资格实践技能考试湖南省首席考官,《中华胃肠外科杂志》《中国普通外科杂志》《中华炎性肠病杂志》《中华结直肠疾病电子杂志》《实用肿瘤杂志》《中国现代手术学杂志》《结直肠肛门外科》《医学临床研究》编委,《中华医学杂志》审稿专家。擅长胃、结直肠肛门疾病的诊治,腹腔镜下胃肠道手术及超低位直肠癌根治保肛手术,在胃肠道肿瘤综合治疗、习惯性便秘、成人巨结肠、炎性肠病、各种复杂性痔、肛瘘、直肠脱垂和腹壁疝及复杂性肠瘘等疾病诊治方面有深入研究。获国家*科研成果三等奖 1 项,省市科技成果进步奖 7 项。承担省级科研项目4 项。主编学术专著 2 部,参编学术专著 7 部,发表各种医学论文 70 余篇。
魏 东 医学博士,主任医师、教授、博士研究生导师,中国人民解放军联勤保障部队第 989 医院全军肛肠外科研究所所长。全军结直肠病学专业委员会主任委员,中国医师协会理事,中国医师协会肛肠医师分会副会长兼总干事,中国医师协会肛肠医师分会临床指南工作委员会主任委员,中国医师协会肛肠医师分会青年委员会委员,中国医疗保健国际交流促进会结直肠分会副主任委员,《解放军医学杂志》《中华胃肠外科杂志》《世界华人消化杂志》《中华结直肠疾病电子杂志》编委。先后承担国家科技重大专项、军区后勤科研计划重点项目国家重点基础研究计划(973 计划)、中华国际医学交流基金专项、河南省科技攻关项目等重点课题 10 项;获军队医疗成果一等奖 1 项,河南省科技进步一等奖 1 项,军队医疗成果二等奖1项,军队科技进步二等奖1项,河南省科技进步二等奖6项;发明专利17项;荣立二等功 1 次,2018 年荣获“中国医师奖”,2017 年荣获“白求恩式好医生”提名奖,多次被评为“全国百强名医”。享受国务院政府特殊津贴。连续 3 次获军队转业技术优秀人才二类岗位津贴。撰写专著 7 部;发表论文 70 余篇,其中 SCI 收载论文 28 篇(单篇Z高影响因子 23.29)、中华系列期刊论文 26 篇、核心期刊 30 篇。
上 篇 慢性便秘概论第 1 章 慢性便秘临床基础一、概念及流行病学二、发病机制三、辅助检查四、诊断和鉴别诊断第 2 章 慢性便秘治疗一、微生态治疗与医学营养干预二、药物治疗三、生物反馈治疗四、精神心理治疗五、中医中药治疗六、慢性便秘的外科治疗七、其他治疗第 3 章 儿童慢性便秘一、定义和诊断标准二、流行病学三、病因和发病机制四、临床特点及分型五、诊断和鉴别诊断六、治疗下 篇 慢性便秘研究及诊治进展第 4 章 慢性便秘基础研究进展节 五羟色胺在胃肠道运动中的作用 一、蠕动反射和 5-HT二、5-HT 能神经元在调控基本胃肠道运动中发挥重要作用三、5-HT 和胃肠道的运动第二节 DNA 甲基化修饰与胃肠道疾病一、DNA 甲基化二、CpG 二核苷酸与 CpG 岛 三、DNA 甲基化与胃肠道疾病四、总结与展望第三节 TRPA1 在结肠动力研究中的作用 一、瞬时受体电位通道超家族简介二、TRPA1 的特殊结构及其特性三、TRPA1 在结肠动力调控中的作用第四节 TRPV1 参与胃肠动力调节的研究进展一、TRP 通道家族二、TRPV1 的结构三、TRPV1 的活化四、TRPV1 的胃肠道分布五、TRPV1 在胃肠动力调节中的作用六、展望第 5 章 慢性便秘发病机制研究进展一、CSTC 的肠动力改变 二、CSTC 的肠神经系统研究 三、间质 Cajal 细胞与 CSTC四、孕激素与孕激素受体五、导泻剂与 CSTC 第 6 章 慢性便秘影像诊断进展一、动态 MR 排便造影诊断出口梗阻型便秘二、胶囊式测压系统在消化道传输功能测定中的应用第 7 章 慢性便秘的外科治疗进展 节 慢传输型便秘外科治疗进展一、慢传输型便秘肠功能检查方法和评估二、STC 的外科治疗三、腹腔镜在 STC 中的应用及难点问题四、结论第二节 顽固性混合型便秘的外科创新术式——金陵术一、设计“金陵术”的背景二、金陵术的手术适应证三、金陵术操作技术和步骤四、金陵术手术后常见并发症及治疗对策五、金陵术围术期处理六、金陵术相关研究第三节 慢传输型便秘合并成人巨结肠的手术治疗一、诊断标准二、术前评估三、术式选择第四节 慢性出口梗阻型便秘手术治疗进展 手术方式第 8 章 慢性便秘中西医结合诊疗策略及相关进展节 慢性便秘的分度论治与中西医结合诊疗策略 一、便秘的定义及诊断缺乏统一的标准二、便秘患者普遍存在不同程度的精神心理异常三、便秘手术方式无固定标准四、便秘的手术时机常常被延误五、便秘术后综合治疗不足六、《2017 版便秘的分度与临床策略专家共识》的特点七、中西医综合诊疗模式实践第二节 慢性便秘中西医结合诊疗策略及临床实践一、流行病学二、中西医认识三、中西医结合诊断策略与进展四、中西医结合治疗策略与进展五、中医辨治老年性便秘的临床实践六、中医治疗直肠前突型便秘的临床实践七、中西医结合治疗盆底松弛型便秘的临床实践八、首荟通便胶囊治疗便秘的临床实践第 9 章 慢性便秘生物反馈与电刺激研究进展 节 排便功能障碍型便秘的生物反馈治疗进展一、排便功能障碍型便秘的诊断和分型二、排便功能障碍型便秘的生物反馈治疗三、排便功能障碍型便秘的电刺激治疗第二节 慢性便秘骶神经调节治疗 一、SNM 的发展史二、SNM 的机制研究三、SNM 的刺激神经选择四、SNM 的操作方法五、SNM 治疗慢性便秘进展六、SNM 安全性第三节 盆底功能失调型便秘的生物反馈治疗一、临床评估二、心理和饮食辅助治疗三、疗效评估第 10 章 肠道菌群与慢性便秘关系的研究进展一、肠道菌群概述二、慢性便秘中肠道菌群的改变三、慢性便秘中肠道菌群代谢产物的变化四、慢性便秘菌群改变的机制五、脑 - 肠 - 菌群轴与慢性便秘的发生六、慢性便秘的微生态治疗七、小结附录 专家共识及相关指南附录 A 中国慢性便秘诊治指南(2013,武汉)附录 B 便秘外科诊治指南(2016)附录 C 中国慢性便秘专家共识意见(2019,广州)附录 D 2017 版便秘的分度与临床策略专家共识附录 E Rome Ⅳ—Functional GI Disorders: Disorders of Gut-Brain Interaction
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