局部麻醉药

Brand: 世界图书出版公司    Sold By: EM China
局部麻醉药
局部麻醉药
局部麻醉药
局部麻醉药

局部麻醉药

Brand: 世界图书出版公司    Sold By: EM China
$56.76 In Stock
Item can be returned in its original condition for a full refund or replacement within 30 days of receipt.
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October2024
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October2024
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局部麻醉药

局部麻醉药

$56.76

编辑推荐局部麻醉药在临床麻醉和疼痛治疗中的地位越来越重要,但局麻药的药理作用较为特殊,不同局麻药的作用也各有特点。对局部组织的尤其是神经组织的影响如何等等都是十分重要的问题。因此本书是一本把局麻药的药理学与临床麻醉紧密结合,能在理论上和临床实践中指导帮助合理用药的专业参考书。 内容简介...
Product Details

编辑推荐
局部麻醉药在临床麻醉和疼痛治疗中的地位越来越重要,但局麻药的药理作用较为特殊,不同局麻药的作用也各有特点。对局部组织的尤其是神经组织的影响如何等等都是十分重要的问题。因此本书是一本把局麻药的药理学与临床麻醉紧密结合,能在理论上和临床实践中指导帮助合理用药的专业参考书。 
内容简介
局部麻醉药在临床麻醉和疼痛治疗中的地位越来越重要,但局麻药的药理作用较为特殊,不同局麻药的作用也各有特点。对局部组织尤其是神经组织的影响如何,局部应用后吸收、分布、代谢、排泄的影响因素有哪些,吸收后的全身影响和毒副作用大小如何,在不同年龄和疾病状态下局麻药作用和副作用的变化如何,怎样按药代动力学和药效动力学原理指导临床安全有效应用局麻药,都是十分重要的问题。因此,迫切需要一本把局麻药的药理学与临床麻醉紧密结合,能在理论上和临床实践中指导帮助合理用药的专业参考书。李士通、庄心良主编的《局部麻醉药(精) 》共分为20章,较为系统地介绍了局部麻醉药的发展历史、作用机理、局麻药在不同人群及不同部位麻醉方法中的应用等方面的基础知识以及新理论和新进展。本书能为广大临床麻醉医师和疼痛治疗医师*全面深入地了解局部麻醉药相关的理论和临床应用提供有价值的参考。
作者简介
上海市麻醉学会委员,中华针灸学会针刺麻醉理事会理事,中华医学会麻醉学分会常务委员,中华麻醉学杂志编委,临床麻醉学杂志编委,国际麻醉学与危急医学杂志常务编委,医学新知杂志常务编委,上海市卫生系统高评委委员。
麻醉药复合应用的基础和临床研究
主要研究不同的麻醉方法、麻醉药及麻醉辅助药物复合应用对病人生理功能的影响,尤其是对特殊病人的影响。
实验研究:从整体动物实验和离体细胞等不同水平研究麻醉药复合应用对循环等功能的影响及其机制。
目  录
在线试读
第4章 局部麻醉药的药代动力学
  节 药代动力学的基本原理
药代动力学(pharmacokinetics)简称药代学,是药理学的重要组成部分。从广义上讲,泛指研究药物的体内过程即机体对药物的吸收、分布、生物转化和排泄过程及其量变规律。狭义的药代学则是指以数学模型和公式,研究体内药物随时间的量变规律。 
一、房室模型 
房室(compartment)是由具有相近的药物转运速率的器官、组织组合而成。同一房室内各部分的药物处于动态平衡。房室仅是按药物转运动力学特征划分的抽象模型,并不代表解剖或生理上的固定结构或成分。同一房室可由不同的器官或组织组成,而同一器官的不同结构或组织,可能分属不同的房室。此外,不同的药物,其房室模型及组成均可不同。运用房室模型,可将机体视为由一个或多个房室组成的系统,从而将复杂的分布过程模型化。
当某药物在体内各部位间均有较高及相近的转运速率时,可在体内迅速达到分布平衡,则该药物属单房室模型。属于单房室模型的药物,在体内达分布平衡后,其血药浓度只受吸收和消除的影响。当某药物在体内不同部位问转运速率存在较大差异时,则将血液及其他血液供应丰富并具有较高转运速率的部分,称为中央室,而把其余部分划归周边室,并可依次再分为周边室、第二周边室等,此即多室模型。根据划分的房室数,相应称为二室模型、三室模型等。属于多室模型的药物,其首先在中央室范围内达分布平衡。然后再与周边室间达到分布平衡,因此其血药浓度除受吸收和消除的影响外,在室间未达分布平衡前,还受分布的影响。

Shipping Overview: 

Shipping: Standard Domestic Shipping within the United States charges USD 4.99. Standard International Shipping from United Kingdom and Germany to the United States charges 14.99. 

Order Processing: Please allow 1-2 business days for order processing and preparation before shipment. 

Domestic Shipping: Orders within the U.S. are shipped via USPS or FedEx, depending on the origin of the product. The average transit time is 3-7 business days. 

International Shipping: Currently, we only ship within the USA. 

Tracking Information: Every order is trackable. You will receive a tracking number once your order has been shipped. Products may be shipped from various global fulfillment centers.

Shipping Delays: 

Please note that shipping times may vary due to factors beyond our control, such as weather conditions, natural disasters, or peak holiday periods. While we strive to ensure timely delivery, the exact arrival time cannot be guaranteed and is managed by the shipping carrier.

Shipping Options:

  • Standard Delivery: Most orders are shipped within 3-7 business days. Larger items may utilize LTL shipping for safe handling.

  • Handling Time: We handle shipments on business days (Monday - Friday), with a preparation time of 1-2 days.

  • Additional Charges: Some items require additional shipping charges due to their size, weight, or special handling. These charges are specified on the product pages and are not eligible for shipping discounts.

  • Exclusions: Gift cards, packaging, taxes, and prior purchases do not count toward the minimum purchase requirement for free shipping. This offer is valid only for shipments to U.S. addresses, including Puerto Rico.

Delivery Details:

  • Estimates: Standard shipping within the US typically takes 3-7 business days. These are estimates and not guarantees.

  • Shipping Restrictions: We ship to all 50 states, Washington, DC, U.S. territories, and APO/FPO/DPO addresses. Shipping options vary based on the delivery address.

  • Remote Areas: Shipments to remote areas may incur additional charges or require pickup from a nearby shipping partner’s location.

Shipping Confirmation:

You will receive a shipping confirmation email with a tracking number as soon as your order is dispatched. If you do not receive this email immediately, please be assured that your items will arrive within the estimated delivery window provided at checkout.

Order Modifications:

If you need to cancel or modify your order, please contact our customer support immediately.

Issues with Delivery:

If your order shows as delivered but you have not received it, please contact the shipping carrier directly to resolve the issue. For persistent problems, contact our customer service at cs@everymarket.com.

Customer Support:

Our team is available 24/7 to assist you with any questions or concerns regarding your order. We are committed to ensuring a smooth shopping experience.

Return & Refund Policy Overview

Please review our return and refund policies below to ensure a smooth transaction process.

Return Policy

  • Duration: You have 30 days from receiving your item to initiate a return.

  • Condition: Items must be unworn, unwashed, with original tags and packaging intact.

  • Shipping Costs: Customers are responsible for return shipping costs.

  • Packaging: Ensure returned items are well-packaged to avoid damage during transit.

  • Tracking: Use a trackable and insured shipping method as we are not liable for items lost or damaged on return.

  • Initiating a Return: Contact us at cs@everymarket.com to start your return. We will provide a return shipping label and instructions upon approval. Returns without prior approval will not be accepted.

How to Return

  • Method: Returns must be sent back by mail to the address provided in the return instructions.

Return Label

  • Defective Products: Return labels are provided for defective items.

  • Non-Defective Returns: Customers are responsible for obtaining their return shipping label.

Product Conditions for Return

  • Eligible Products: Returns are only accepted for items in new condition.

Nonreturnable Items

Certain items are not eligible for return:

  • Electronic devices after 30 days (e.g., computers, laptops, Kindles)

  • Gift cards, prepaid game cards

  • Perishable goods, live insects, some jewelry, some health and personal care items

  • Customized or personalized products

  • Items with special shipping restrictions

Refund Policy

  • Window: Eligible products may be returned within 30 days of delivery for a refund.

  • Refund Method: Refunds are processed to the original payment method or as store credit for items purchased with gift cards.

  • Processing Time: Refunds are processed within 3-5 business days after we receive the return; please allow additional time for shipping and bank processing.

Claims

Inspect your order upon arrival and report any defects, damages, or incorrect items immediately to allow us to address the issue. For claims, contact our support team with details of the issue.

Exchange Policy

For the quickest service, return your original item and place a new order for the desired product once your return is accepted.

Return Address

EveryMarket Customer Service 2101 E Terra Ln, O'Fallon, MO 63366

Customer Support

Available 24/7 for any questions or assistance needed:

  • Phone: +1 636-312-5925

  • Email: cs@everymarket.com

 

编辑推荐
局部麻醉药在临床麻醉和疼痛治疗中的地位越来越重要,但局麻药的药理作用较为特殊,不同局麻药的作用也各有特点。对局部组织的尤其是神经组织的影响如何等等都是十分重要的问题。因此本书是一本把局麻药的药理学与临床麻醉紧密结合,能在理论上和临床实践中指导帮助合理用药的专业参考书。 
内容简介
局部麻醉药在临床麻醉和疼痛治疗中的地位越来越重要,但局麻药的药理作用较为特殊,不同局麻药的作用也各有特点。对局部组织尤其是神经组织的影响如何,局部应用后吸收、分布、代谢、排泄的影响因素有哪些,吸收后的全身影响和毒副作用大小如何,在不同年龄和疾病状态下局麻药作用和副作用的变化如何,怎样按药代动力学和药效动力学原理指导临床安全有效应用局麻药,都是十分重要的问题。因此,迫切需要一本把局麻药的药理学与临床麻醉紧密结合,能在理论上和临床实践中指导帮助合理用药的专业参考书。李士通、庄心良主编的《局部麻醉药(精) 》共分为20章,较为系统地介绍了局部麻醉药的发展历史、作用机理、局麻药在不同人群及不同部位麻醉方法中的应用等方面的基础知识以及新理论和新进展。本书能为广大临床麻醉医师和疼痛治疗医师*全面深入地了解局部麻醉药相关的理论和临床应用提供有价值的参考。
作者简介
上海市麻醉学会委员,中华针灸学会针刺麻醉理事会理事,中华医学会麻醉学分会常务委员,中华麻醉学杂志编委,临床麻醉学杂志编委,国际麻醉学与危急医学杂志常务编委,医学新知杂志常务编委,上海市卫生系统高评委委员。
麻醉药复合应用的基础和临床研究
主要研究不同的麻醉方法、麻醉药及麻醉辅助药物复合应用对病人生理功能的影响,尤其是对特殊病人的影响。
实验研究:从整体动物实验和离体细胞等不同水平研究麻醉药复合应用对循环等功能的影响及其机制。
目  录
在线试读
第4章 局部麻醉药的药代动力学
  节 药代动力学的基本原理
药代动力学(pharmacokinetics)简称药代学,是药理学的重要组成部分。从广义上讲,泛指研究药物的体内过程即机体对药物的吸收、分布、生物转化和排泄过程及其量变规律。狭义的药代学则是指以数学模型和公式,研究体内药物随时间的量变规律。 
一、房室模型 
房室(compartment)是由具有相近的药物转运速率的器官、组织组合而成。同一房室内各部分的药物处于动态平衡。房室仅是按药物转运动力学特征划分的抽象模型,并不代表解剖或生理上的固定结构或成分。同一房室可由不同的器官或组织组成,而同一器官的不同结构或组织,可能分属不同的房室。此外,不同的药物,其房室模型及组成均可不同。运用房室模型,可将机体视为由一个或多个房室组成的系统,从而将复杂的分布过程模型化。
当某药物在体内各部位间均有较高及相近的转运速率时,可在体内迅速达到分布平衡,则该药物属单房室模型。属于单房室模型的药物,在体内达分布平衡后,其血药浓度只受吸收和消除的影响。当某药物在体内不同部位问转运速率存在较大差异时,则将血液及其他血液供应丰富并具有较高转运速率的部分,称为中央室,而把其余部分划归周边室,并可依次再分为周边室、第二周边室等,此即多室模型。根据划分的房室数,相应称为二室模型、三室模型等。属于多室模型的药物,其首先在中央室范围内达分布平衡。然后再与周边室间达到分布平衡,因此其血药浓度除受吸收和消除的影响外,在室间未达分布平衡前,还受分布的影响。

Shipping Overview: 

Shipping: Standard Domestic Shipping within the United States charges USD 4.99. Standard International Shipping from United Kingdom and Germany to the United States charges 14.99. 

Order Processing: Please allow 1-2 business days for order processing and preparation before shipment. 

Domestic Shipping: Orders within the U.S. are shipped via USPS or FedEx, depending on the origin of the product. The average transit time is 3-7 business days. 

International Shipping: Currently, we only ship within the USA. 

Tracking Information: Every order is trackable. You will receive a tracking number once your order has been shipped. Products may be shipped from various global fulfillment centers.

Shipping Delays: 

Please note that shipping times may vary due to factors beyond our control, such as weather conditions, natural disasters, or peak holiday periods. While we strive to ensure timely delivery, the exact arrival time cannot be guaranteed and is managed by the shipping carrier.

Shipping Options:

  • Standard Delivery: Most orders are shipped within 3-7 business days. Larger items may utilize LTL shipping for safe handling.

  • Handling Time: We handle shipments on business days (Monday - Friday), with a preparation time of 1-2 days.

  • Additional Charges: Some items require additional shipping charges due to their size, weight, or special handling. These charges are specified on the product pages and are not eligible for shipping discounts.

  • Exclusions: Gift cards, packaging, taxes, and prior purchases do not count toward the minimum purchase requirement for free shipping. This offer is valid only for shipments to U.S. addresses, including Puerto Rico.

Delivery Details:

  • Estimates: Standard shipping within the US typically takes 3-7 business days. These are estimates and not guarantees.

  • Shipping Restrictions: We ship to all 50 states, Washington, DC, U.S. territories, and APO/FPO/DPO addresses. Shipping options vary based on the delivery address.

  • Remote Areas: Shipments to remote areas may incur additional charges or require pickup from a nearby shipping partner’s location.

Shipping Confirmation:

You will receive a shipping confirmation email with a tracking number as soon as your order is dispatched. If you do not receive this email immediately, please be assured that your items will arrive within the estimated delivery window provided at checkout.

Order Modifications:

If you need to cancel or modify your order, please contact our customer support immediately.

Issues with Delivery:

If your order shows as delivered but you have not received it, please contact the shipping carrier directly to resolve the issue. For persistent problems, contact our customer service at cs@everymarket.com.

Customer Support:

Our team is available 24/7 to assist you with any questions or concerns regarding your order. We are committed to ensuring a smooth shopping experience.

Return & Refund Policy Overview

Please review our return and refund policies below to ensure a smooth transaction process.

Return Policy

  • Duration: You have 30 days from receiving your item to initiate a return.

  • Condition: Items must be unworn, unwashed, with original tags and packaging intact.

  • Shipping Costs: Customers are responsible for return shipping costs.

  • Packaging: Ensure returned items are well-packaged to avoid damage during transit.

  • Tracking: Use a trackable and insured shipping method as we are not liable for items lost or damaged on return.

  • Initiating a Return: Contact us at cs@everymarket.com to start your return. We will provide a return shipping label and instructions upon approval. Returns without prior approval will not be accepted.

How to Return

  • Method: Returns must be sent back by mail to the address provided in the return instructions.

Return Label

  • Defective Products: Return labels are provided for defective items.

  • Non-Defective Returns: Customers are responsible for obtaining their return shipping label.

Product Conditions for Return

  • Eligible Products: Returns are only accepted for items in new condition.

Nonreturnable Items

Certain items are not eligible for return:

  • Electronic devices after 30 days (e.g., computers, laptops, Kindles)

  • Gift cards, prepaid game cards

  • Perishable goods, live insects, some jewelry, some health and personal care items

  • Customized or personalized products

  • Items with special shipping restrictions

Refund Policy

  • Window: Eligible products may be returned within 30 days of delivery for a refund.

  • Refund Method: Refunds are processed to the original payment method or as store credit for items purchased with gift cards.

  • Processing Time: Refunds are processed within 3-5 business days after we receive the return; please allow additional time for shipping and bank processing.

Claims

Inspect your order upon arrival and report any defects, damages, or incorrect items immediately to allow us to address the issue. For claims, contact our support team with details of the issue.

Exchange Policy

For the quickest service, return your original item and place a new order for the desired product once your return is accepted.

Return Address

EveryMarket Customer Service 2101 E Terra Ln, O'Fallon, MO 63366

Customer Support

Available 24/7 for any questions or assistance needed:

  • Phone: +1 636-312-5925

  • Email: cs@everymarket.com

 

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