中医方证代谢组学研究进展.2021年卷 王喜军编 科学出版社 9787030741004

Brand: 科学出版社    Sold By: EM China
中医方证代谢组学研究进展.2021年卷 王喜军编 科学出版社 9787030741004
中医方证代谢组学研究进展.2021年卷 王喜军编 科学出版社 9787030741004
中医方证代谢组学研究进展.2021年卷 王喜军编 科学出版社 9787030741004
中医方证代谢组学研究进展.2021年卷 王喜军编 科学出版社 9787030741004

中医方证代谢组学研究进展.2021年卷 王喜军编 科学出版社 9787030741004

Brand: 科学出版社    Sold By: EM China
$92.95 In Stock
Item can be returned in its original condition for a full refund or replacement within 30 days of receipt.
Ships from China, Arrives in 7-14 business days
Delivery:
16
October2024
-
25
October2024
Delivery guarantee
$5 Credit If Delayed
Full Refund If Item Is Damaged
15-Day Full Refund If No Updates
30-Day Full Refund If Not Delivered

100% Satisfaction Guarantee

Amazing Value

Fast Shipping

Expert Customer Service

中医方证代谢组学研究进展.2021年卷 王喜军编 科学出版社 9787030741004

中医方证代谢组学研究进展.2021年卷 王喜军编 科学出版社 9787030741004

$92.95

Product Details

温馨提示

尊敬的客户您好:

      根据北京国税局规定,开票需提供贵司单位名称以及税号,若您需要发票,请您下单时务必留言抬头及税号,便于为您开具发票。

       本店所有图书均为正版,请放心订购!

  • 加急可选择顺丰快递
  • 本店所有图书不支持国外件,如需寄往国外,下单前需要和客服联系后才可以,感谢您的配合。
  • 由于我店所有图书的专业性较强,确保正版(所有图书的信息均以收到的实物书的版权页为准),不支持七天无理由退货,如运输过程中产生的损坏,可以换书,但不可以退,敬请知悉,谢谢
  • 电子版一经发送,无法撤回,更不支持七天无理由退货!不支持七天无理由退货!不支持七天无理由退货!
  • 有疑问请致电客服:13801017046  赵老师

  • 由于图书的特殊性和稀缺性,部分图书为古旧图书和绝版书,大部分图书会出现销价高于原定价(由于当当的特殊规定,而填写的定价则会是高于原定价的金额)的情况产生,如不能确定是否高于原定价销售,可咨询客服,如未咨询下单,则表示同意此商品的销价,敬请知悉!!!
  • 祝您购物愉快!!!

  •                                                       华清智鉴图书专营店

商品详情



商品参数

 

中医方证代谢组学研究进展.2021年卷
ISBN 9787030741004
定价 288
作者  著;王喜军 编; 译;
开本 16
装帧 圆脊精装
页数 408
出版时间 2023年02月
出版社 科学出版社



内容介绍


本书系统介绍了2020年度中医方证代谢组学相关研究进展。以中医方证代谢组学研究内容为主线,系统介绍了基于生物标志物的方剂有效性评价、肠道菌群代谢及中药调控机制、中药体内显效成分分析、中药体内显效成分的效应机制、中药毒性评价及解毒机制、中药质量等领域的研究进 展。书中例证翔实,图表充分,能够带领读者快速、全面地了解中医方证代谢组学研究领域的最新进展。

目录


目录
Chinmedomics Builds a Bridge from Traditional to Modern Research of Traditional
Chinese Medicine(代序)
前言
第一章 中医方证代谢组学研究 1
第一节 证候/ 疾病生物标志物发现与表征 1
第二节 中药效应精准评价 3
第三节 中药药效物质研究 6
第四节 代表性研究——基于临床和动物实验整合的中医方证代谢组学研究揭示茵陈蒿汤治疗黄疸的体内药效物质及潜在作用靶点 7
参考文献 34
第二章 基于生物标志物的方剂有效性研究 37
第一节 多柔比星诱导心力衰竭大鼠生物标志物及四逆汤有效性研究 37
第二节 寒凝血瘀证模型大鼠生物标志物及当归四逆汤有效性研究 50
第三节 失血性贫血大鼠生物标志物及当归补血汤有效性研究 65
第四节 血虚证小鼠生物标志物及当归补血汤有效性研究 75
第五节 子宫异常出血大鼠生物标志物及桃红四物汤有效性研究 87
第六节 糖尿病下肢缺血小鼠生物标志物及补脏通络方有效性研究 95
第七节 糖尿病脑病db/db小鼠生物标志物及黄连解毒汤有效性研究 105
第八节 失眠大鼠模型生物标志物及酸枣仁汤有效性研究 115
第九节 葛根芩连汤治疗急性肺损伤药效评价及作用机制研究 124
参考文献 141
第三章 基于肠道菌群的中药及有效成分作用机制研究 145
第一节 基于“肠- 心轴”途径探究保元汤抗病理性心肌肥大作用机制 146
第二节 基于肠道菌群及其代谢的抗衰老片干预高脂饮食诱导肥胖的作用机制研究 159
第三节 基于肠道菌群及其代谢的灵芝孢子油增强小鼠免疫功能的潜在作用机制研究 169
第四节 整合代谢表型与肠道菌群的荷叶碱降尿酸潜在调控机制研究 184
参考文献 202
第四章 中药体内显效成分研究 204
第一节 复方皂矾丸治疗贫血小鼠模型的体内显效成分研究 204
第二节 精制冠心片治疗冠心病大鼠模型的体内显效成分研究 214
第三节 罗珍胶囊治疗肝火亢盛型高血压大鼠模型的体内显效成分研究 226
第四节 芍药甘草汤治疗神经病理性疼痛的体内显效成分研究 249
第五节 广陈皮治疗高脂血症大鼠模型的体内显效成分研究 268
第六节 广西产桑叶治疗高脂血症的体内显效成分研究 275
参考文献 280
第五章 基于代谢组学的中药有效成分的效应机制研究 281
第一节 京尼平苷治疗阳黄证的作用机制研究 282
第二节 小檗碱抑制胰腺癌的作用机制研究 288
第三节 人参皂苷Rb1 抗衰老的作用机制研究 295
第四节 黄芩素抗神经炎症的作用机制研究 304
第五节 虎杖苷治疗高尿酸血症的作用机制研究 313
第六节 咖啡酸延长果蝇寿命的作用机制研究 320
第七节 葛根多糖治疗高脂血症的作用机制研究 329
参考文献 336
第六章 基于代谢组学的有毒中药毒性及解毒机制研究 337
第一节 云南白药配伍环境下草乌毒性的代谢组学研究 337
第二节 甘遂醋炙减毒存效作用机制研究 347
第三节 甘草制雷公藤降低肝毒性的作用机制研究 358
参考文献 366
第七章 基于代谢组学的中药质量评价研究 367
第一节 丹参发汗过程中代谢物的变化研究 367
第二节 不同基原蝉蜕药材质量一致性评价研究 374
第三节 三个生态型肉苁蓉的品质变异及其潜在调控机制研究 382
第四节 不同盐胁迫下金银花的代谢组学研究 388
第五节 车前子及其盐制品的利尿作用研究 395
第六节 酒蒸女贞子整体化学转化与关键标志物研究 400
参考文献 408

Shipping Overview: 

Shipping: Standard Domestic Shipping within the United States charges USD 4.99. Standard International Shipping from United Kingdom and Germany to the United States charges 14.99. 

Order Processing: Please allow 1-2 business days for order processing and preparation before shipment. 

Domestic Shipping: Orders within the U.S. are shipped via USPS or FedEx, depending on the origin of the product. The average transit time is 3-7 business days. 

International Shipping: Currently, we only ship within the USA. 

Tracking Information: Every order is trackable. You will receive a tracking number once your order has been shipped. Products may be shipped from various global fulfillment centers.

Shipping Delays: 

Please note that shipping times may vary due to factors beyond our control, such as weather conditions, natural disasters, or peak holiday periods. While we strive to ensure timely delivery, the exact arrival time cannot be guaranteed and is managed by the shipping carrier.

Shipping Options:

  • Standard Delivery: Most orders are shipped within 3-7 business days. Larger items may utilize LTL shipping for safe handling.

  • Handling Time: We handle shipments on business days (Monday - Friday), with a preparation time of 1-2 days.

  • Additional Charges: Some items require additional shipping charges due to their size, weight, or special handling. These charges are specified on the product pages and are not eligible for shipping discounts.

  • Exclusions: Gift cards, packaging, taxes, and prior purchases do not count toward the minimum purchase requirement for free shipping. This offer is valid only for shipments to U.S. addresses, including Puerto Rico.

Delivery Details:

  • Estimates: Standard shipping within the US typically takes 3-7 business days. These are estimates and not guarantees.

  • Shipping Restrictions: We ship to all 50 states, Washington, DC, U.S. territories, and APO/FPO/DPO addresses. Shipping options vary based on the delivery address.

  • Remote Areas: Shipments to remote areas may incur additional charges or require pickup from a nearby shipping partner’s location.

Shipping Confirmation:

You will receive a shipping confirmation email with a tracking number as soon as your order is dispatched. If you do not receive this email immediately, please be assured that your items will arrive within the estimated delivery window provided at checkout.

Order Modifications:

If you need to cancel or modify your order, please contact our customer support immediately.

Issues with Delivery:

If your order shows as delivered but you have not received it, please contact the shipping carrier directly to resolve the issue. For persistent problems, contact our customer service at cs@everymarket.com.

Customer Support:

Our team is available 24/7 to assist you with any questions or concerns regarding your order. We are committed to ensuring a smooth shopping experience.

Return & Refund Policy Overview

Please review our return and refund policies below to ensure a smooth transaction process.

Return Policy

  • Duration: You have 30 days from receiving your item to initiate a return.

  • Condition: Items must be unworn, unwashed, with original tags and packaging intact.

  • Shipping Costs: Customers are responsible for return shipping costs.

  • Packaging: Ensure returned items are well-packaged to avoid damage during transit.

  • Tracking: Use a trackable and insured shipping method as we are not liable for items lost or damaged on return.

  • Initiating a Return: Contact us at cs@everymarket.com to start your return. We will provide a return shipping label and instructions upon approval. Returns without prior approval will not be accepted.

How to Return

  • Method: Returns must be sent back by mail to the address provided in the return instructions.

Return Label

  • Defective Products: Return labels are provided for defective items.

  • Non-Defective Returns: Customers are responsible for obtaining their return shipping label.

Product Conditions for Return

  • Eligible Products: Returns are only accepted for items in new condition.

Nonreturnable Items

Certain items are not eligible for return:

  • Electronic devices after 30 days (e.g., computers, laptops, Kindles)

  • Gift cards, prepaid game cards

  • Perishable goods, live insects, some jewelry, some health and personal care items

  • Customized or personalized products

  • Items with special shipping restrictions

Refund Policy

  • Window: Eligible products may be returned within 30 days of delivery for a refund.

  • Refund Method: Refunds are processed to the original payment method or as store credit for items purchased with gift cards.

  • Processing Time: Refunds are processed within 3-5 business days after we receive the return; please allow additional time for shipping and bank processing.

Claims

Inspect your order upon arrival and report any defects, damages, or incorrect items immediately to allow us to address the issue. For claims, contact our support team with details of the issue.

Exchange Policy

For the quickest service, return your original item and place a new order for the desired product once your return is accepted.

Return Address

EveryMarket Customer Service 2101 E Terra Ln, O'Fallon, MO 63366

Customer Support

Available 24/7 for any questions or assistance needed:

  • Phone: +1 636-312-5925

  • Email: cs@everymarket.com

 

温馨提示

尊敬的客户您好:

      根据北京国税局规定,开票需提供贵司单位名称以及税号,若您需要发票,请您下单时务必留言抬头及税号,便于为您开具发票。

       本店所有图书均为正版,请放心订购!

  • 加急可选择顺丰快递
  • 本店所有图书不支持国外件,如需寄往国外,下单前需要和客服联系后才可以,感谢您的配合。
  • 由于我店所有图书的专业性较强,确保正版(所有图书的信息均以收到的实物书的版权页为准),不支持七天无理由退货,如运输过程中产生的损坏,可以换书,但不可以退,敬请知悉,谢谢
  • 电子版一经发送,无法撤回,更不支持七天无理由退货!不支持七天无理由退货!不支持七天无理由退货!
  • 有疑问请致电客服:13801017046  赵老师

  • 由于图书的特殊性和稀缺性,部分图书为古旧图书和绝版书,大部分图书会出现销价高于原定价(由于当当的特殊规定,而填写的定价则会是高于原定价的金额)的情况产生,如不能确定是否高于原定价销售,可咨询客服,如未咨询下单,则表示同意此商品的销价,敬请知悉!!!
  • 祝您购物愉快!!!

  •                                                       华清智鉴图书专营店

商品详情



商品参数

 

中医方证代谢组学研究进展.2021年卷
ISBN 9787030741004
定价 288
作者  著;王喜军 编; 译;
开本 16
装帧 圆脊精装
页数 408
出版时间 2023年02月
出版社 科学出版社



内容介绍


本书系统介绍了2020年度中医方证代谢组学相关研究进展。以中医方证代谢组学研究内容为主线,系统介绍了基于生物标志物的方剂有效性评价、肠道菌群代谢及中药调控机制、中药体内显效成分分析、中药体内显效成分的效应机制、中药毒性评价及解毒机制、中药质量等领域的研究进 展。书中例证翔实,图表充分,能够带领读者快速、全面地了解中医方证代谢组学研究领域的最新进展。

目录


目录
Chinmedomics Builds a Bridge from Traditional to Modern Research of Traditional
Chinese Medicine(代序)
前言
第一章 中医方证代谢组学研究 1
第一节 证候/ 疾病生物标志物发现与表征 1
第二节 中药效应精准评价 3
第三节 中药药效物质研究 6
第四节 代表性研究——基于临床和动物实验整合的中医方证代谢组学研究揭示茵陈蒿汤治疗黄疸的体内药效物质及潜在作用靶点 7
参考文献 34
第二章 基于生物标志物的方剂有效性研究 37
第一节 多柔比星诱导心力衰竭大鼠生物标志物及四逆汤有效性研究 37
第二节 寒凝血瘀证模型大鼠生物标志物及当归四逆汤有效性研究 50
第三节 失血性贫血大鼠生物标志物及当归补血汤有效性研究 65
第四节 血虚证小鼠生物标志物及当归补血汤有效性研究 75
第五节 子宫异常出血大鼠生物标志物及桃红四物汤有效性研究 87
第六节 糖尿病下肢缺血小鼠生物标志物及补脏通络方有效性研究 95
第七节 糖尿病脑病db/db小鼠生物标志物及黄连解毒汤有效性研究 105
第八节 失眠大鼠模型生物标志物及酸枣仁汤有效性研究 115
第九节 葛根芩连汤治疗急性肺损伤药效评价及作用机制研究 124
参考文献 141
第三章 基于肠道菌群的中药及有效成分作用机制研究 145
第一节 基于“肠- 心轴”途径探究保元汤抗病理性心肌肥大作用机制 146
第二节 基于肠道菌群及其代谢的抗衰老片干预高脂饮食诱导肥胖的作用机制研究 159
第三节 基于肠道菌群及其代谢的灵芝孢子油增强小鼠免疫功能的潜在作用机制研究 169
第四节 整合代谢表型与肠道菌群的荷叶碱降尿酸潜在调控机制研究 184
参考文献 202
第四章 中药体内显效成分研究 204
第一节 复方皂矾丸治疗贫血小鼠模型的体内显效成分研究 204
第二节 精制冠心片治疗冠心病大鼠模型的体内显效成分研究 214
第三节 罗珍胶囊治疗肝火亢盛型高血压大鼠模型的体内显效成分研究 226
第四节 芍药甘草汤治疗神经病理性疼痛的体内显效成分研究 249
第五节 广陈皮治疗高脂血症大鼠模型的体内显效成分研究 268
第六节 广西产桑叶治疗高脂血症的体内显效成分研究 275
参考文献 280
第五章 基于代谢组学的中药有效成分的效应机制研究 281
第一节 京尼平苷治疗阳黄证的作用机制研究 282
第二节 小檗碱抑制胰腺癌的作用机制研究 288
第三节 人参皂苷Rb1 抗衰老的作用机制研究 295
第四节 黄芩素抗神经炎症的作用机制研究 304
第五节 虎杖苷治疗高尿酸血症的作用机制研究 313
第六节 咖啡酸延长果蝇寿命的作用机制研究 320
第七节 葛根多糖治疗高脂血症的作用机制研究 329
参考文献 336
第六章 基于代谢组学的有毒中药毒性及解毒机制研究 337
第一节 云南白药配伍环境下草乌毒性的代谢组学研究 337
第二节 甘遂醋炙减毒存效作用机制研究 347
第三节 甘草制雷公藤降低肝毒性的作用机制研究 358
参考文献 366
第七章 基于代谢组学的中药质量评价研究 367
第一节 丹参发汗过程中代谢物的变化研究 367
第二节 不同基原蝉蜕药材质量一致性评价研究 374
第三节 三个生态型肉苁蓉的品质变异及其潜在调控机制研究 382
第四节 不同盐胁迫下金银花的代谢组学研究 388
第五节 车前子及其盐制品的利尿作用研究 395
第六节 酒蒸女贞子整体化学转化与关键标志物研究 400
参考文献 408

Shipping Overview: 

Shipping: Standard Domestic Shipping within the United States charges USD 4.99. Standard International Shipping from United Kingdom and Germany to the United States charges 14.99. 

Order Processing: Please allow 1-2 business days for order processing and preparation before shipment. 

Domestic Shipping: Orders within the U.S. are shipped via USPS or FedEx, depending on the origin of the product. The average transit time is 3-7 business days. 

International Shipping: Currently, we only ship within the USA. 

Tracking Information: Every order is trackable. You will receive a tracking number once your order has been shipped. Products may be shipped from various global fulfillment centers.

Shipping Delays: 

Please note that shipping times may vary due to factors beyond our control, such as weather conditions, natural disasters, or peak holiday periods. While we strive to ensure timely delivery, the exact arrival time cannot be guaranteed and is managed by the shipping carrier.

Shipping Options:

  • Standard Delivery: Most orders are shipped within 3-7 business days. Larger items may utilize LTL shipping for safe handling.

  • Handling Time: We handle shipments on business days (Monday - Friday), with a preparation time of 1-2 days.

  • Additional Charges: Some items require additional shipping charges due to their size, weight, or special handling. These charges are specified on the product pages and are not eligible for shipping discounts.

  • Exclusions: Gift cards, packaging, taxes, and prior purchases do not count toward the minimum purchase requirement for free shipping. This offer is valid only for shipments to U.S. addresses, including Puerto Rico.

Delivery Details:

  • Estimates: Standard shipping within the US typically takes 3-7 business days. These are estimates and not guarantees.

  • Shipping Restrictions: We ship to all 50 states, Washington, DC, U.S. territories, and APO/FPO/DPO addresses. Shipping options vary based on the delivery address.

  • Remote Areas: Shipments to remote areas may incur additional charges or require pickup from a nearby shipping partner’s location.

Shipping Confirmation:

You will receive a shipping confirmation email with a tracking number as soon as your order is dispatched. If you do not receive this email immediately, please be assured that your items will arrive within the estimated delivery window provided at checkout.

Order Modifications:

If you need to cancel or modify your order, please contact our customer support immediately.

Issues with Delivery:

If your order shows as delivered but you have not received it, please contact the shipping carrier directly to resolve the issue. For persistent problems, contact our customer service at cs@everymarket.com.

Customer Support:

Our team is available 24/7 to assist you with any questions or concerns regarding your order. We are committed to ensuring a smooth shopping experience.

Return & Refund Policy Overview

Please review our return and refund policies below to ensure a smooth transaction process.

Return Policy

  • Duration: You have 30 days from receiving your item to initiate a return.

  • Condition: Items must be unworn, unwashed, with original tags and packaging intact.

  • Shipping Costs: Customers are responsible for return shipping costs.

  • Packaging: Ensure returned items are well-packaged to avoid damage during transit.

  • Tracking: Use a trackable and insured shipping method as we are not liable for items lost or damaged on return.

  • Initiating a Return: Contact us at cs@everymarket.com to start your return. We will provide a return shipping label and instructions upon approval. Returns without prior approval will not be accepted.

How to Return

  • Method: Returns must be sent back by mail to the address provided in the return instructions.

Return Label

  • Defective Products: Return labels are provided for defective items.

  • Non-Defective Returns: Customers are responsible for obtaining their return shipping label.

Product Conditions for Return

  • Eligible Products: Returns are only accepted for items in new condition.

Nonreturnable Items

Certain items are not eligible for return:

  • Electronic devices after 30 days (e.g., computers, laptops, Kindles)

  • Gift cards, prepaid game cards

  • Perishable goods, live insects, some jewelry, some health and personal care items

  • Customized or personalized products

  • Items with special shipping restrictions

Refund Policy

  • Window: Eligible products may be returned within 30 days of delivery for a refund.

  • Refund Method: Refunds are processed to the original payment method or as store credit for items purchased with gift cards.

  • Processing Time: Refunds are processed within 3-5 business days after we receive the return; please allow additional time for shipping and bank processing.

Claims

Inspect your order upon arrival and report any defects, damages, or incorrect items immediately to allow us to address the issue. For claims, contact our support team with details of the issue.

Exchange Policy

For the quickest service, return your original item and place a new order for the desired product once your return is accepted.

Return Address

EveryMarket Customer Service 2101 E Terra Ln, O'Fallon, MO 63366

Customer Support

Available 24/7 for any questions or assistance needed:

  • Phone: +1 636-312-5925

  • Email: cs@everymarket.com

 

Oops!

Sorry, it looks like some products are not available in selected quantity.

OK